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Development of the atrial septum
  1. Robert H Anderson
  1. Correspondence to Professor Robert H Anderson, Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne, Tyne and Wear NE1 3BZ, UK. sejjran{at}

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To the Editor,

I read with interest the review presented by Asrress et al in your series ‘Education in Heart’.1 I was disappointed to find figure 1 representing a spurious concept of development. Although the concept is to be found in many textbooks of cardiac embryology, it is not necessarily correct. Asrress et al go part way to explaining its deficiency when they state “Infolding of the atrial wall on the right aspect of the septum primum produces the septum secundum”. This mechanism of infolding was described by Rose as long ago as the end of the 19th century.2 The problem with the …

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  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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