Streamlining cardiovascular clinical trials to improve efficiency and generalisability

Faiez Zannad; Marc A Pfeffer; Deepak L Bhatt; Denise E Bonds; Jeffrey S Borer; Gonzalo Calvo-Rojas; Louis Fiore; Lars H Lund; David Madigan; Aldo Pietro Maggioni; Catherine M Meyers; Yves Rosenberg; Tabassome Simon; Wendy Gattis Stough; Andrew Zalewski; Nevine Zariffa; Robert Temple

doi:10.1136/heartjnl-2017-311191

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Streamlining cardiovascular clinical trials to improve efficiency and generalisability

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Faiez Zannad Clinical Investigation Center, Centre Hospitalier Universitaire de Nancy, Nancy, France PubMed articles Google scholar articles
Marc A Pfeffer Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
Deepak L Bhatt Brigham and Women's Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
Denise E Bonds National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA PubMed articles Google scholar articles
Jeffrey S Borer The Howard Gilman Institute, New York, New York, USA State University of New York Downstate Medical Center, Brooklyn, New York, USA PubMed articles Google scholar articles
Gonzalo Calvo-Rojas Department of Clinical Pharmacology, Hospital Clínic, University of Barcelona, Barcelona, Spain PubMed articles Google scholar articles
Louis Fiore Department of Veterans Affairs, Cooperative Studies Program, Boston, Massachusetts, USA PubMed articles Google scholar articles
Lars H Lund Department of Medicine, Unit of Cardiology, Karolinska Institute, Stockholm, Sweden PubMed articles Google scholar articles
David Madigan Department of Statistics, Columbia University, New York, New York, USA PubMed articles Google scholar articles
Aldo Pietro Maggioni ANMCO Research Center, Florence, Italy PubMed articles Google scholar articles
Catherine M Meyers National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, Maryland, USA PubMed articles Google scholar articles
Yves Rosenberg National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA PubMed articles Google scholar articles
Tabassome Simon Assistance Publique-Hôpitaux de Paris, Saint Antoine Hospital, Paris, France Université Pierre et Marie Curie, Paris, France PubMed articles Google scholar articles
Wendy Gattis Stough Campbell University College of Pharmacy and Health Sciences, Research Triangle Park, North Carolina, USA PubMed articles Google scholar articles
Andrew Zalewski Glaxo Smith Kline, King of Prussia, Pennsylvania, USA PubMed articles Google scholar articles
Nevine Zariffa AstraZeneca, Cambridge, UK PubMed articles Google scholar articles
Robert Temple Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, Maryland, USA PubMed articles Google scholar articles

Correspondence to Professor Faiez Zannad, Clinical Investigation Center, Centre Hospitalier Universitaire de Nancy, UniversitÃ© de Lorraine and INI-CRCT (F-CRIN); Institut Lorrain du Coeur et des Vaisseaux, Nancy 54500, France; f.zannad{at}chru-nancy.fr

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Zannad F, Pfeffer MA, Bhatt DL, et al

Streamlining cardiovascular clinical trials to improve efficiency and generalisability

Heart 2017;103:1156-1162.

Publication history

Received January 15, 2017
Revised March 7, 2017
Accepted March 19, 2017
First published April 28, 2017.

Online issue publication

July 14, 2017

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