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Bicuspid aortic valves and intracranial aneurysms: more than an incidental coexistence?
  1. Evaldas Girdauskas
  1. Correspondence to Dr Evaldas Girdauskas, Department of Cardiovascular Surgery, University Heart Center Hamburg, Martinistraße 52, 20251 Hamburg, Germany; egirdauskas{at}

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We read with great interest the manuscript by Egbe and coauthors from Mayo Clinic published in Heart.1 The authors focused on a clinically relevant manifestation of intracranial aneurysms (IAs) in patients diagnosed with a bicuspid aortic valve disease (BAV). A large institutional BAV cohort was retrospectively analysed while identifying those patients with BAV who had brain imaging with MRA. A total of 52 patients (7.7%) with IA were identified which were associated with seven adverse events during the follow-up (two aneurysm ruptures, four coil embolisations and three aneurysm enlargements >1 mm). Based on these findings, the authors stated an increased IA prevalence in patients with BAV, especially in those presenting with a concomitant aortic coarctation (ie, 12.9%). Furthermore, a clinically relevant association was revealed between proximal BAV-associated aortopathy and IA occurrence which may indicate a common pathophysiologic pathway in the aneurysm formation. …

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  • Contributors Yskert von Kodolitsch contributed substantially to the final version of this editorial.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.

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