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Original research article
Platelet count and mean platelet volume predict outcome in adults with Eisenmenger syndrome
  1. Agustin C Martin-Garcia1,2,3,
  2. Deepa RJ Arachchillage2,4,
  3. Aleksander Kempny1,2,
  4. Rafael Alonso-Gonzalez1,2,
  5. Ana Martin-Garcia3,
  6. Anselm Uebing1,2,
  7. Lorna Swan1,2,
  8. Stephen J Wort1,2,5,
  9. Laura C Price1,5,
  10. Colm McCabe1,5,
  11. Pedro Luis Sanchez6,
  12. Konstantinos Dimopoulos1,2,
  13. Michael A Gatzoulis1,2
  1. 1 Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Brompton Hospital, London, UK
  2. 2 NIHR Cardiovascular Biomedical Research Unit, Royal Brompton and Hammersmith Hospitals, London, UK
  3. 3 Cardiology Department, University Hospital of Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL-CIBERCV), Salamanca, Spain
  4. 4 Department of Haematology, Royal Brompton Hospital, London, UK
  5. 5 National Heart and Lung Institute, Imperial College School of Medicine, London, UK
  6. 6 Centre for Haematology, Imperial College London, London, UK
  1. Correspondence to Dr Konstantinos Dimopoulos, Adult Congenital Heart Centre, Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, SW3 6NP London, UK; k.dimopoulos02{at}gmail.com

Footnotes

  • KD and MAG contributed equally.

  • Contributors ACM, DRJA, KD and MAG planned the study and participated in the design, analysis, writing and revision of the manuscript. AK, RAG, AMG, AU, LS, SJW, LCP, CM and PLS participated in the revision of the manuscript.

  • Competing interests ACM has received support from the Instituto de Investigacion Biomedica de Salamanca (IBSAL). AK, KD, SJW and MAG from the Royal Brompton Hospital have received unrestricted educational and research grants and acted as consultants for Bayer, Pfizer, Actelion and GSK. LCP has received research funding and educational grants from GSK and educational grants from Actelion; no other relationships or activities that could appear to have influenced the submitted work.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • KD and MAG contributed equally.

  • Contributors ACM, DRJA, KD and MAG planned the study and participated in the design, analysis, writing and revision of the manuscript. AK, RAG, AMG, AU, LS, SJW, LCP, CM and PLS participated in the revision of the manuscript.

  • Competing interests ACM has received support from the Instituto de Investigacion Biomedica de Salamanca (IBSAL). AK, KD, SJW and MAG from the Royal Brompton Hospital have received unrestricted educational and research grants and acted as consultants for Bayer, Pfizer, Actelion and GSK. LCP has received research funding and educational grants from GSK and educational grants from Actelion; no other relationships or activities that could appear to have influenced the submitted work.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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