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Original research article
Impact of surgery on presence and dimensions of anatomical isthmuses in tetralogy of Fallot
  1. Gijsbert F L Kapel1,
  2. Sergio Laranjo2,
  3. Nico A Blom1,
  4. Mark G Hazekamp3,
  5. Martin J Schalij1,
  6. Margot M Bartelings2,
  7. Monique R M Jongbloed1,2,
  8. Katja Zeppenfeld1
  1. 1Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
  2. 2Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
  3. 3Department of Cardiac Surgery, Leiden University Medical Center, Leiden, The Netherlands
  1. Correspondence to Professor Katja Zeppenfeld, Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands; K.Zeppenfeld{at}lumc.nl

Footnotes

  • Contributors GFLK: conceived and designed the research, acquired data, performed statistical analysis, drafted the manuscript, made critical revision of the manuscript for intellectual content, responsible for the overall content as guarantor, submitted the study. SL: conceived and designed the research, acquired data, performed statistical analysis, made critical revision of the manuscript for intellectual content. NAB and MGH: conceived and designed the research, made critical revision of the manuscript for intellectual content. MJS: made critical revision of the manuscript for intellectual content. MMB: conceived and designed the research, acquired data, made critical revision of the manuscript for intellectual content. MRMJ and KZ: conceived and designed the research, performed statistical analysis, drafted the manuscript, made critical revision of the manuscript for intellectual content, handled supervision, responsible for the overall content as guarantor.

  • Funding The Department of Cardiology Leiden receives unrestricted research and fellowship grants from Edward Lifesciences, Boston Scientific, Medtronic and Biotronik.

  • Competing interests None declared.

  • Ethics approval This study was undertaken in accordance with the local ethics committee and the Dutch regulation for the proper use of human tissue for medical research purposes.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Contributors GFLK: conceived and designed the research, acquired data, performed statistical analysis, drafted the manuscript, made critical revision of the manuscript for intellectual content, responsible for the overall content as guarantor, submitted the study. SL: conceived and designed the research, acquired data, performed statistical analysis, made critical revision of the manuscript for intellectual content. NAB and MGH: conceived and designed the research, made critical revision of the manuscript for intellectual content. MJS: made critical revision of the manuscript for intellectual content. MMB: conceived and designed the research, acquired data, made critical revision of the manuscript for intellectual content. MRMJ and KZ: conceived and designed the research, performed statistical analysis, drafted the manuscript, made critical revision of the manuscript for intellectual content, handled supervision, responsible for the overall content as guarantor.

  • Funding The Department of Cardiology Leiden receives unrestricted research and fellowship grants from Edward Lifesciences, Boston Scientific, Medtronic and Biotronik.

  • Competing interests None declared.

  • Ethics approval This study was undertaken in accordance with the local ethics committee and the Dutch regulation for the proper use of human tissue for medical research purposes.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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