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Conclusions are inappropriate due to the big discrepancies between groups
  1. Saul G Myerson
  1. Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK
  1. Correspondence to Prof Saul G Myerson, Department of Cardiovascular Medicine, University of Oxford, Oxford OX1 2JD, UK; saul.myerson{at}

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It is a shame that good research questions such as the one addressed by the paper of Bongiovanni et al 1 are hampered by inappropriate conclusions from the authors using a weak study design. Comparing observational groups that underwent transcutaneous aortic valve implantation (TAVI) or balloon aortic valvuloplasty (BAV) is fraught with difficulty, as the types of patients that are selected for the procedures are markedly different. In particular, those with poor life expectancy for a variety of (cardiac and non-cardiac) reasons are much more likely to …

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  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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