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Evaluation of aortic regurgitation with cardiac magnetic resonance imaging: a systematic review
  1. James C Lee1,
  2. Kelley R Branch1,
  3. Christian Hamilton-Craig1,2,3,
  4. Eric V Krieger1,4
  1. 1 Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA
  2. 2 Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia
  3. 3 Department of Cardiology, Heart & Lung Institute, The Prince Charles Hospital, Brisbane, Queensland, Australia
  4. 4 Seattle Adult Congenital Heart Service, University of Washington School of Medicine, Seattle, Washington, USA
  1. Correspondence to Dr  Eric V Krieger, Seattle Adult Congenital Heart Service, University of Washington School of Medicine, Seattle, WA 98195, USA; eKrieger{at}


This review summaries the utility, application and data supporting use of cardiac magnetic resonance imaging (CMR) to evaluate and quantitate aortic regurgitation. We systematically searched Medline and PubMed for original research articles published since 2000 that provided data on the quantitation of aortic regurgitation by CMR and identified 11 articles for review. Direct aortic measurements using phase contrast allow quantitation of volumetric flow across the aortic valve and are highly reproducible and accurate compared with echocardiography. However, this technique requires diligence in prescribing the correct imaging planes in the aorta. Volumetric analytic techniques using differences in ventricular volumes are also highly accurate but less than phase contrast techniques and only accurate when concomitant valvular disease is absent. Comparison of both aortic and ventricular data for internal data verification ensures fidelity of aortic regurgitant data. CMR data can be applied to many types of aortic valve regurgitation including combined aortic stenosis with regurgitation, congenital valve diseases and post-transcatheter valve placement. CMR also predicts those patients who progress to surgery with high overall sensitivity and specificity. Future studies of CMR in patients with aortic regurgitation to quantify the incremental benefit over echocardiography as well as prediction of cardiovascular events are warranted.

  • cardiac magnetic resonance(cmr)imaging
  • advanced cardiac imaging
  • aortic regurgitation
  • transcatheter valve interventions

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  • Contributors JCL, KRB, CH-C, EVK contributed to the drafting of the study and critical review.

  • Competing interests Dr CH-C has been an speaker for Siemens, Merck and Edwards. Dr KRB has received research support from Bayer, Astellas. Ad board and Jansen. Drs JCL and EVK have no conflicts to report.

  • Provenance and peer review Commissioned; externally peer reviewed.

  • Data sharing statement None declared.