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Use of genotype-guided warfarin for anticoagulation control in patients undergoing hip or knee arthroplasty
Dosing of warfarin can be inconsistent for a variety of clinical reasons and may also be influenced by patient genotype. Significant interest exists in finding more effective ways to dose warfarin but previous studies of genotype dosing have shown varied results. The Genetic Informatics Trial (GIFT) of Warfarin to Prevent DVT seeks to determine whether genotype-guided dosing improves the safety of warfarin initiation, defined as days …
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