Purpose The aim of this study was to determine whether TAPSE and RV Sa in ECHO correlate with RV ejection fraction in CMR and whether they are useful markers in diagnosis of RV systolic dysfunction.
Methods 49 patients with repaired tetralogy of Fallot, aged 7 to 53 years (median mean 21) were selected retrospectively. They underwent ECHO and CMR at the Freeman Hospital from January 2008 to June 2016 within 4 months of each other.
Two groups were identified: the first group of 24 patients with normal RV systolic function with ejection fraction ≥45% in CMR and a second group of 25 patients who had impaired RV systolic function with ejection fraction <45%.
Results There was a positive relationship between TAPSE and RV Sa (R=0.65, P-value=0.05).
Median TAPSE was 1.31 (mean 1.39) in the first group and 1.57 (mean 1.57) in the second group. Median RV Sa was 7.64 (mean 8.24) in the first group and 8.84 (mean 9.53) in the second group.
The left ventricle ejection fraction was preserved even with impaired RV ejection fraction (P-value=0.017).
Conclusion This study demonstrated that TAPSE and RV Sa are reproducible measurements of RV systolic function.
We did not prove a correlation between TAPSE, RV Sa and RV ejection fraction. We concluded that these measurements are not clinically useful markers of RV systolic dysfunction in patients with repaired TOF. Further studies on larger population involving RV longitudinal strain are necessary to investigate its relationship with RV ejection fraction in CMR.
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