Proprotein convertase subtilisin/kexin 9 inhibitors in reducing cardiovascular outcomes: a systematic review and meta-analysis

Heyue Du; Xiaodan Li; Na Su; Ling Li; Xiaoting Hao; Haihui Gao; Joey Sum-Wing Kwong; Per Olav Vandvik; Xueli Yang; Imola Nemeth; Ify R Mordi; Qianrui Li; Longhao Zhang; Li Rao; Chim C Lang; Jianshu Li; Haoming Tian; Sheyu Li

doi:10.1136/heartjnl-2019-314763

Article info

Cardiac risk factors and prevention

Original research article

Proprotein convertase subtilisin/kexin 9 inhibitors in reducing cardiovascular outcomes: a systematic review and meta-analysis

Authors

Heyue Du Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China West China School of Medicine, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Xiaodan Li Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Na Su Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Ling Li Chinese Evidence-based Medicine Center and CREAT group, West China Hospital, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Xiaoting Hao Department of Neurology, West China Hospital, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Haihui Gao Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China Department of Rheumatology and Clinical Immunology, The Affiliated Hospital of Qingdao University, Qingdao, China PubMed articles Google scholar articles
Joey Sum-Wing Kwong Jockey Club School of Public Health andPrimary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong, China PubMed articles Google scholar articles
Per Olav Vandvik Norwegian Institute of Public Health, Oslo, Norway Department of Medicine, Innlandet Hospital Trust, Gjøvik, Norway PubMed articles Google scholar articles
Xueli Yang Departmentof Epidemiology, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China PubMed articles Google scholar articles
Imola Nemeth Division of Population Health & Genomics, Ninewells Hospital, University of Dundee, Dundee, UK PubMed articles Google scholar articles
Ify R Mordi Division of Molecular & Clinical Medicine, Ninewells Hospital, University of Dundee, Dundee, UK PubMed articles Google scholar articles
Qianrui Li Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China Institute of Health Informatics, University College London, London, UK Health Data Research UK London, University College London, London, UK PubMed articles Google scholar articles
Longhao Zhang Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Li Rao Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Chim C Lang Division of Molecular & Clinical Medicine, Ninewells Hospital, University of Dundee, Dundee, UK PubMed articles Google scholar articles
Jianshu Li Department of Biomedical Polymer and Artificial Organs, College of Polymer Science and Engineering, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Haoming Tian Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China PubMed articles Google scholar articles
Sheyu Li Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China Division of Population Health & Genomics, Ninewells Hospital, University of Dundee, Dundee, UK PubMed articles Google scholar articles

Correspondence to Dr Sheyu Li, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China and Division of Population Health & Genomics, Ninewells Hospital and School of Medicine, University of Dundee, Dundee, DD1 9SY, Scotland, UK; lisheyu{at}gmail.com

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Citation

Du H, Li X, Su N, et al

Proprotein convertase subtilisin/kexin 9 inhibitors in reducing cardiovascular outcomes: a systematic review and meta-analysis

Heart 2019;105:1149-1159.

Publication history

Received January 16, 2019
Revised January 28, 2019
Accepted January 30, 2019
First published March 6, 2019.

Online issue publication

January 18, 2021

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