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Original research article
Segmental aortic stiffness in patients with bicuspid aortic valve compared with first-degree relatives
  1. Guillaume Goudot1,
  2. Tristan Mirault2,3,
  3. Aude Rossi2,
  4. Samuel Zarka2,
  5. Juliette Albuisson2,3,
  6. Paul Achouh4,
  7. Mathieu Pernot1,
  8. Emmanuel Messas2,3
  1. 1 Institut Langevin, INSERM U979, ESPCI Paris, CNRS UMR 7587, PSL Research University, Paris, France
  2. 2 Pôle cardiovasculaire, Centre de Référence des Maladies Vasculaires Rares, Hôpital Européen Georges Pompidou, APHP, Paris, France
  3. 3 INSERM U970 PARCC, Paris Descartes University – USPC Sorbonne Paris Cité University, Paris, France
  4. 4 Service de chirurgie cardiovasculaire, Hôpital Européen Georges Pompidou, APHP, Paris, France
  1. Correspondence to Professor Emmanuel Messas, Centre National de Référence Maladies Vasculaires Rares, Hôpital européen Georges-Pompidou, Paris 75015, France; emmanuel.messas{at}aphp.fr

Footnotes

  • Contributors GG, AR, SZ, EM carried out the dedicated consultations and collected the data. GG, TM, JA, PA, MP analysed the data. GG and TM performed the statistical analysis. GG, TM wrote the manuscript. JA, PA, MP, EM proof-read the manuscript. EM organised this study. He supervised the cardiac ultrasounds. EM gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy and integrity of any part of the work are appropriately investigated and resolved.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval The institutional review board (Local Ethic Committee) approved this study.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Contributors GG, AR, SZ, EM carried out the dedicated consultations and collected the data. GG, TM, JA, PA, MP analysed the data. GG and TM performed the statistical analysis. GG, TM wrote the manuscript. JA, PA, MP, EM proof-read the manuscript. EM organised this study. He supervised the cardiac ultrasounds. EM gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy and integrity of any part of the work are appropriately investigated and resolved.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval The institutional review board (Local Ethic Committee) approved this study.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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