Article Text

Download PDFPDF
Methodological considerations for potential improvement of this study
  1. H Pendell Meyers1,
  2. Stephen W Smith2
  1. 1 Emergency Medicine, Stony Brook University Hospital, Stony Brook, New York, USA
  2. 2 Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota, USA
  1. Correspondence to Dr H Pendell Meyers, Emergency Medicine, Stony Brook University Hospital, Stony Brook, NY 11794, USA; harvey.p.meyers{at}vanderbilt.edu

Statistics from Altmetric.com

To the Editor

Nestelberger et al 1 performed a prospective observational study of patients with left bundle branch block (LBBB) and suspected acute coronary syndrome (ACS) to further elucidate the optimal strategy of evaluation for this population. Unfortunately there are several methodological problems which prevent the authors from realising the full clinical potential of their dataset.

First, the study uses the diagnosis of acute myocardial infarction (AMI) as the primary outcome against which the ECG findings are judged, implying both that the role of the ECG is to diagnose all types of AMI, and that the authors expect such accuracy. This logic runs counter to the role of …

View Full Text

Footnotes

  • Contributors HPM and SWS both contributed to content, organisation, and editing of the manuscript.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

  • Patient consent for publication Not required.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Coronary artery disease
    Thomas Nestelberger Louise Cullen Bertil Lindahl Tobias Reichlin Jaimi H Greenslade Evangelos Giannitsis Michael Christ Beata Morawiec Oscar Miro Francisco Javier Martín-Sánchez Desiree Nadine Wussler Luca Koechlin Raphael Twerenbold William Parsonage Jasper Boeddinghaus Maria Rubini Gimenez Christian Puelacher Karin Wildi Tobias Buerge Patrick Badertscher Jeanne DuFaydeLavallaz Ivo Strebel Lukas Croton Garnet Bendig Stefan Osswald John William Pickering Martin Than Christian Mueller on behalf of the APACE, ADAPT and TRAPID-AMI Investigators Petra Hillinger Karin Grimm Ursina Honegger Nicolas Schaerli Nikola Kozhuharov Samyut Shrestha Claudia Stelzig Michael Freese Zaid Sabti Joan Walter Lorraine Sazgary Caroline Kulangara Kathrin Meissner Deborah Mueller Beatriz Lopez Emilio Salgado Esther Rodríguez Adrada Damian Kawecki Jiri Parenica Eva Ganovska Katharina Rentsch Andreas Buser Jens Lohrmann Roland Bingisser Samyut Shrestha Fabio Stallone Roger Abaecherli James Mccord Richard Nowak Richard Body Christopher R Defilippi Robert H Christenson Mauro Panteghini Mario Plebani Franck Verschuren John French Silvia Weiser Carina Dinkel Dagmar I Keller Nicolas Geigy