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Original research article
Cardiac output changes from prior to pregnancy to post partum using two non-invasive techniques
  1. Giulia Masini1,
  2. Lin F Foo1,
  3. Jérôme Cornette2,
  4. Jasmine Tay1,
  5. Dimitris Rizopoulos3,
  6. Carmel M McEniery4,
  7. Ian B Wilkinson4,
  8. Christoph C Lees1,5
  1. 1 Department of Surgery and Cancer, Imperial College London, London, UK
  2. 2 Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
  3. 3 Department of Biostatistics, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
  4. 4 Experimental Medicine and Immunotherapeutics, Addenbrooke’s Hospital, Cambridge, UK
  5. 5 Department of Development and Regeneration, KU Leuven, Leuven, Belgium
  1. Correspondence to Dr Christoph C Lees, Department of Surgery and Cancer, Imperial College London, London W12 0HS, UK; christoph.lees{at}nhs.net

Footnotes

  • Contributors CCL and JC have contributed to conception and design of the study. GM, LFF and JT have acquired the data. JC and DR have analysed the data. GM has drafted the manuscript. CCL, IBW and CMM have critically revised the manuscript. CCL is responsible for the overall content as guarantor.

  • Funding This work was supported by Action Medical Research, Samsung Healthcare, Imperial College Healthcare Trust Charities, Imperial College BRC and Genesis Research Trust. The funding sources had no involvement in the study design, collection of data and writing the article.

  • Competing interests CCL reports grants from Action Medical Research, grants and non-financial support from Samsung Healthcare, grants from Imperial College Healthcare Trust Charities and grants from Imperial College BRC, outside the submitted work.

  • Patient consent Obtained.

  • Ethics approval The two prospective observational studies were approved by the National Research Ethics Committee (’CONCEIVE': East of Scotland Research Ethics Service, REC reference 14/ES/1046; ’PRECEPT': National Research Ethics Service Committee London Riverside, REC reference 15/LO/0341).

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Contributors CCL and JC have contributed to conception and design of the study. GM, LFF and JT have acquired the data. JC and DR have analysed the data. GM has drafted the manuscript. CCL, IBW and CMM have critically revised the manuscript. CCL is responsible for the overall content as guarantor.

  • Funding This work was supported by Action Medical Research, Samsung Healthcare, Imperial College Healthcare Trust Charities, Imperial College BRC and Genesis Research Trust. The funding sources had no involvement in the study design, collection of data and writing the article.

  • Competing interests CCL reports grants from Action Medical Research, grants and non-financial support from Samsung Healthcare, grants from Imperial College Healthcare Trust Charities and grants from Imperial College BRC, outside the submitted work.

  • Patient consent Obtained.

  • Ethics approval The two prospective observational studies were approved by the National Research Ethics Committee (’CONCEIVE': East of Scotland Research Ethics Service, REC reference 14/ES/1046; ’PRECEPT': National Research Ethics Service Committee London Riverside, REC reference 15/LO/0341).

  • Provenance and peer review Not commissioned; externally peer reviewed.

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