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COVID-19 has become a global pandemic which has had a major impact on hundreds of countries across the world. In less than 6 months, we have seen millions of people infected by the virus and over a quarter of a million deaths. The speed and rapidity of the spread of COVID-19 has left many countries scrambling to initiate public health interventions and to cope with the impact on healthcare provision in hospitals. In spite of this, the majority of people who are infected have either no symptoms or mild self-limiting disease. Understanding and identifying those at risk of severe manifestations or death has therefore become an imperative.
Our understanding of COVID-19 continues to evolve, but it was clear early on that, like other viral pandemics, the severity of disease and mortality are greatest in older people. Going beyond age alone, further exploration of the comorbidities has suggested an influence of coexisting cardiovascular disease. In this issue of Heart, Li and colleagues present a systematic review and meta-analysis of studies looking at the outcomes of patients with COVID-19 in relation to their history of cardiovascular disease and the presence of myocardial injury.1 This a rapidly evolving field and it is amazing to observe that this systematic review has already distilled data from over 3000 patients in as little as a 3-month period; such is the global scientific impetus to share knowledge. Their findings …
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Contributors DEN: writing and preparation of the original draft of the manuscript. KR: writing, review and editing.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests KR, as associate editor for BMJ Heart, receives personal fees.
Patient and public involvement Patients and/or the public were not involved in the design, conduct, reporting or dissemination plans of this research.
Patient consent for publication Not required.
Provenance and peer review Commissioned; internally peer reviewed.
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- Healthcare delivery, economics and global health