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The Authors’ reply: Release of troponin after exercise stress test in hypertrophic cardiomyopathy
  1. Gilbert E Cramer,
  2. Marc A Brouwer
  1. Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands
  1. Correspondence to Gilbert E Cramer, Cardiology, Radboud University Medical Center, Nijmegen 6500 HB, Netherlands; etienne.cramer{at}

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The Authors' reply

We thank Dr Dimitrow and his colleagues for their interest in our work on postexercise troponin rises in patients with clinical hypertrophic cardiomyopathy (HCM) using mutation carriers as controls.1 Concerns were expressed with regard to methodological issues.

First, a single 6-hour postexercise troponin measurement was mentioned as a shortcoming of our study. It was suggested that additional 12-hour, 18-hour and 24-hour sampling should also have been performed. We agree that additional sampling could have …

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  • Contributors Both authors contributed significantly to the present work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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