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Response to eLetter: Fascinating helpful article, but how typical were the patients with DCM and what does this tell us?
  1. Lynne Martina Millar1,
  2. Zephryn Fanton1,
  3. Gherardo Finocchiaro1,
  4. Gabriel Sanchez-Fernandez1,
  5. Harshil Dhutia1,
  6. Aneil Malhotra1,2,
  7. Ahmed Merghani1,
  8. Michael Papadakis1,
  9. Elijah R Behr1,
  10. Nick Bunce1,
  11. David Oxborough3,
  12. Matthew Reed1,
  13. Jamie O'Driscoll4,
  14. Maria Teresa Tome Esteban1,
  15. Andrew D'Silva1,
  16. Gerry Carr-White5,
  17. Jessica Webb5,6,
  18. Rajan Sharma1,
  19. Sanjay Sharma1
  1. 1 Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust and Institute of Molecular and Clinical Sciences St. George's University of London, London, UK
  2. 2 Division of Cardiovascular Sciences, University of Manchester, Division of Cardiovascular Sciences, Manchester, UK
  3. 3 Research Institute of Sports and Exercise Science, Liverpool John Moores University, Liverpool, UK
  4. 4 Canterbury Christ Church University, Canterbury, UK
  5. 5 Department of Cardiology, Guy's and St. Thomas' Foundation Trust, London, UK
  6. 6 King's College London School of Medical Education, London, UK
  1. Correspondence to Professor Sanjay Sharma, Institute of Cardiovascular and Cell Sciences, St George’s University of London, London SW17 0RE, UK; sasharma{at}sgul.ac.uk

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The Authors’ reply

We are grateful to Dr Stuart1 for his interest in our paper.2 We agree entirely that our dilated cardiomyopathy (DCM) cohort were indeed highly selected. Most individuals with DCM do not have the capacity to exercise intensively and would not fit in the differential diagnosis of an athlete’s heart with borderline or mildly reduced left ventricular (LV) ejection fraction. For the purposes of this study, we sought to identify individuals with a mild form of DCM who were motivated to and could exercise intensively for a prolonged …

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Footnotes

  • Twitter @drlynnemillar, @harshil_dhutia, @MichaelPapadak2, @SSharmacardio

  • Contributors LMM and SS drafted the letter. All the other authors contributed to the revisions.

  • Funding LMM, HD, AMa and GF were funded by research grants from Cardiac Risk in the Young. AD'S and AMe were funded by research grants from the British Heart Foundation.

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, conduct, reporting or dissemination plans of this research.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned; internally peer reviewed.

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