Article Text

Download PDFPDF
Premature ventricular contraction–induced cardiomyopathy entails more than only systolic left ventricular dysfunction
  1. Ferit Onur Mutluer1,
  2. Uğur Canpolat2,
  3. Sing-Chien Yap1
  1. 1 Department of Cardiology, Erasmus University Rotterdam, Rotterdam, The Netherlands
  2. 2 Department of Cardiology, Hacettepe University, Ankara, Turkey
  1. Correspondence to Dr Uğur Canpolat, Department of Cardiology, Hacettepe University, Ankara 06100, Turkey; dru_canpolat{at}

Statistics from

To the Editor

We read with interest the article by Lee et al 1 assessing the potential benefit of a watchful waiting strategy in 100 patients with frequent premature ventricular contractions (PVCs) (>5%/24 hours) and preserved left ventricular ejection fraction (LVEF) of >50%. The most striking result of the current study was the high proportion of patients with spontaneous reduction in PVC frequency during follow-up. In 44% of the patients, spontaneous PVC reduction (<1%/24 hours) was observed at a median follow-up of 15.4 months. Unfortunately, the authors do not provide data on the development of symptoms in the remaining 56% of the cohort with persistent frequent PVCs. Furthermore, the authors focus on systolic LV …

View Full Text


  • Contributors FOM, UC, S-CY: substantial contributions to the conception or design of the work. FOM, UC, S-CY: drafting the work or revising it critically for important intellectual content. FOM, UC, S-CY: final approval of the version published. FOM, UC, S-CY: agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Competing interests UC: proctoring for Abbott, lecturer for Medtronic.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles