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Patient manifested as left ventricular non-compaction
  1. Lili Wang,
  2. Dan Yang,
  3. Yucheng Chen
  1. Cardiology Division, West China Hospital, Sichuan University, Chengdu, China
  1. Correspondence to Dr Yucheng Chen, Cardiology Division, West China Hospital, Sichuan University, Chengdu 610041, China; chenyucheng2003{at}

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Clinical introduction

A woman in her 20s suffering from chest tightness was referred with suspected cardiomyopathy by echocardiogram. No skeletal muscle and mental abnormalities were found. Her mother died of advanced heart failure at the age of 48, but the exact cause of heart failure is unclear. Cardiac magnetic resonance demonstrated normal left ventricular (LV) wall thickness; LV cavity was mildly enlarged (figure 1A); LV ejection fraction (EF) was decreased (EF=44.5%). We found prominent hypertrabeculations at mid-apical portions of the left ventricle (the ratio of the non-compacted to compacted myocardial layers=3.3, figure 1B). Furthermore, patchy non-ischaemic …

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  • LW and DY contributed equally.

  • Contributors All authors contributed to acquisition of clinical and imaging data, ideation and draft of the article.

  • Funding 1·3·5 project for disciplines of excellence–Clinical Research Incubation Project, West China Hospital, Sichuan University (ZYJC18013).

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, conduct, reporting or dissemination plans of this research.

  • Provenance and peer review Not commissioned; internally peer reviewed.