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Augmentation of pulmonary blood flow and cardiac output by non-invasive external ventilation late after Fontan palliation
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  • Published on:
    Biphasic ventilation for failing Fontan physiology
    • Seigo Okada, Pediatrics Japan Community Healthcare Organization, Kyushu Hospital
    • Other Contributors:
      • Jun Muneuchi, Pediatrics
      • Mamie Watanabe, Pediatrics

    Biphasic ventilation for failing Fontan physiology

    Seigo Okada1, MD, PhD, Jun Muneuchi1, MD, PhD, Mamie Watanabe1, MD

    1Department of Pediatrics, Japan Community Healthcare Organization, Kyushu Hospital, 1-8-1, Kishinuora, Yahatanishiku, Kitakyushu, Fukuoka, 806-8501, Japan

    Address correspondence and reprint requests to: Seigo Okada, M.D., Ph.D.
    Department of Pediatrics, Japan Community Healthcare Organization, Kyushu Hospital, 1-8-1, Kishinoura, Yahatanishiku, Kitakyushu, Fukuoka, 806-8501, Japan. Tel: 81-93-641-5111; Fax: 81-93-642-1868; E-mail:; ORCID: 0000-0002-9150-1913

    Dear Editor:
    We read the article by Charla et al.1 with great interest. The authors conducted a phase-contrast magnetic resonance study during biphasic ventilation (BPV) in 10 patients aged 20–34 years who had Fontan circulation and 10 matched control subjects. BPV resulted in significant pulmonary blood flow and cardiac output augmentations in the Fontan group, which suggests the importance of “thoracic pump” in Fontan patients without a subpulmonary ventricle. We appreciate the authors’ efforts to assess the efficacy and feasibility of noninvasive external ventilation for Fontan patients. This is a thoughtfully conducted study, but some issues must be further discussed.
    First, the authors mentioned that the study was the first to describe the impact of BPV in the Fontan population. However, we...

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    Conflict of Interest:
    None declared.