Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial

Annette Marie Maznyczka; Peter McCartney; Patrycja Duklas; Margaret McEntegart; Keith G Oldroyd; John P Greenwood; Douglas Muir; Saqib Chowdhary; Anthony H Gershlick; Clare Appleby; Hany Eteiba; James Cotton; Andrew Wragg; Nick Curzen; R Campbell Tait; Peter MacFarlane; Paul Welsh; Naveed Sattar; Mark C Petrie; Ian Ford; Keith A A Fox; Alex McConnachie; Colin Berry

doi:10.1136/heartjnl-2020-317828

Article info

Coronary artery disease

Original research

Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial

Authors

Annette Marie Maznyczka Department of Cardiology, Golden Jubilee National Hospital, Glasgow, UK British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Peter McCartney Department of Cardiology, Golden Jubilee National Hospital, Glasgow, UK PubMed articles Google scholar articles
Patrycja Duklas Robertson Centre for Biostatistics, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Margaret McEntegart Department of Cardiology, Golden Jubilee National Hospital, Glasgow, UK PubMed articles Google scholar articles
Keith G Oldroyd Department of Cardiology, Golden Jubilee National Hospital, Glasgow, UK British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
John P Greenwood Department of Cardiology, Leeds General Infirmary, Leeds, UK Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Douglas Muir James Cook University Hospital, Middlesbrough, UK PubMed articles Google scholar articles
Saqib Chowdhary Manchester University NHS Foundation Trust, Manchester, UK PubMed articles Google scholar articles
Anthony H Gershlick Division of Cardiology, University of Leicester, Leicester, UK PubMed articles Google scholar articles
Clare Appleby Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, UK PubMed articles Google scholar articles
Hany Eteiba Department of Cardiology, Golden Jubilee National Hospital, Glasgow, UK PubMed articles Google scholar articles
James Cotton Department of Cardiology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, Wolverhampton, UK PubMed articles Google scholar articles
Andrew Wragg Barts and The London Hospital, London, UK PubMed articles Google scholar articles
Nick Curzen Wessex Cardiac Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK PubMed articles Google scholar articles
R Campbell Tait Department of Haematology, Glasgow Royal Infirmary, Glasgow, UK PubMed articles Google scholar articles
Peter MacFarlane Electrocardiology Group, Royal Infirmary, Glasgow, UK PubMed articles Google scholar articles
Paul Welsh British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Naveed Sattar British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Mark C Petrie British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Ian Ford Robertson Centre for Biostatistics, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Keith A A Fox Department of Cardiology, University of Edinburgh and Royal Infirmary of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
Alex McConnachie Robertson Centre for Biostatistics, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
Colin Berry Department of Cardiology, Golden Jubilee National Hospital, Glasgow, UK British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK PubMed articles Google scholar articles
T-TIME (Trial of low-dose adjunctive alTeplase during primary PCI) investigators
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Correspondence to Professor Colin Berry, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8TA, UK; colin.berry{at}glasgow.ac.uk

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Citation

Maznyczka AM, McCartney P, Duklas P T-TIME (Trial of low-dose adjunctive alTeplase during primary PCI) investigators, et al

Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial

Heart 2021;107:299-312.

Publication history

Received July 18, 2020
Revised October 29, 2020
Accepted November 2, 2020
First published January 12, 2021.

Online issue publication

January 08, 2022

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