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  • Pregnancy outcomes in women with a systemic right ventricle and transposition of the great arteries results from the ESC-EORP Registry of Pregnancy and Cardiac disease (ROPAC)

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Congenital heart disease
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Pregnancy outcomes in women with a systemic right ventricle and transposition of the great arteries results from the ESC-EORP Registry of Pregnancy and Cardiac disease (ROPAC)
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  • Published on: 25 May 2021
    Response to: “Pregnancy outcomes in women with a systemic right ventricle and transposition of the great arteries results from the ESC-EORP Registry of Pregnancy and Cardiac disease (ROPAC) by Tutarel et al.
    • Magdalena Lipczyńska, cardiologist National Institute Of Cardiology, Warsaw, Poland
    • Other Contributors:
      • Piotr Szymański, cardiologist
      • Lidia Tomkiewicz-Pająk, cardiologist
      • Olga Trojnarska, Cardiologist
      • Piotr Hoffman, Head of Congenital Heart Disease Department

    We read with great interest the recent results from ESC-EORP
    Registry of Pregnancy and Cardiac disease (ROPAC), concerning pregnancy.
    outcomes in women with systemic right ventricle (sRV) and transposition of the
    great arteries (TGA) by Tutarel et al. (1) In Tutarel et al. analysis HF was the
    most frequent maternal complication (9.1%). These results are concordant
    with our previous observations of 24 pregnancies of women with TGA after
    atrial switch operation and matched non-pregnant controls with TGA after atrial
    redirection. 2 In our series 2 women deteriorated from the functional NYHA
    class I to II after the first pregnancy and one woman in her fourth pregnancy
    deteriorated from class I to III. Tutarel’s results reinforce our conclusion that,
    from a cardiologist’s point of view, pregnancy after the Mustard/Senning
    operation was relatively well-tolerated and safe.
    In ROPAC study the information on tricuspid regurgitation (TR) was collected, but was
    not mandatory. Therefore Tutarel et al. concluded that dedicated studies focusing on
    sRV function and TR are warranted. Our dataset provided relevant information
    on sRV and TR. At baseline, all women had preserved or only mildly reduced
    sRV function estimated by echocardiography before pregnancy and absent or
    mild TR. There were no differences between non-pregnant matched controls
    and pregnant women in sRV function, deg...

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    Conflict of Interest:
    None declared.