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- Published on: 25 May 2021
- Published on: 25 May 2021Response to: “Pregnancy outcomes in women with a systemic right ventricle and transposition of the great arteries results from the ESC-EORP Registry of Pregnancy and Cardiac disease (ROPAC) by Tutarel et al.
We read with great interest the recent results from ESC-EORP
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Registry of Pregnancy and Cardiac disease (ROPAC), concerning pregnancy.
outcomes in women with systemic right ventricle (sRV) and transposition of the
great arteries (TGA) by Tutarel et al. (1) In Tutarel et al. analysis HF was the
most frequent maternal complication (9.1%). These results are concordant
with our previous observations of 24 pregnancies of women with TGA after
atrial switch operation and matched non-pregnant controls with TGA after atrial
redirection. 2 In our series 2 women deteriorated from the functional NYHA
class I to II after the first pregnancy and one woman in her fourth pregnancy
deteriorated from class I to III. Tutarel’s results reinforce our conclusion that,
from a cardiologist’s point of view, pregnancy after the Mustard/Senning
operation was relatively well-tolerated and safe.
In ROPAC study the information on tricuspid regurgitation (TR) was collected, but was
not mandatory. Therefore Tutarel et al. concluded that dedicated studies focusing on
sRV function and TR are warranted. Our dataset provided relevant information
on sRV and TR. At baseline, all women had preserved or only mildly reduced
sRV function estimated by echocardiography before pregnancy and absent or
mild TR. There were no differences between non-pregnant matched controls
and pregnant women in sRV function, deg...Conflict of Interest:
None declared.