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Editorial
Overweight and incident hypertension: does age of onset matter?
  1. Jorge A Wong1,2
  1. 1 Department of Medicine, McMaster University, Hamilton, Ontario, Canada
  2. 2 Population Health Research Institute, Hamilton, Ontario, Canada
  1. Correspondence to Dr Jorge A Wong, Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada; wongjas{at}mcmaster.ca

https://doi.org/10.1136/heartjnl-2021-320771

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    Obesity represents one of the cardiovascular challenges of the twenty-first century.1 2 Obesity is a potent risk factor for the development of hypertension, diabetes and hyperlipidaemia, crucial for the subsequent development of cardiovascular disease.1 2 A greater understanding of the relationship between the timing of the onset of obesity and the development of these risk factors is of importance as it would allow for the tailoring of preventative strategies in populations at the highest risk.

    Prior studies have documented the relationship between the development of obesity in early adulthood and the subsequent risk of hypertension. In an analysis of the Johns Hopkins Precursors Study, development of obesity (body mass index (BMI) ≥30 kg/m2) in young adulthood was associated with an increased risk of subsequent hypertension (HR 4.17, 95% CI 2.34 to 7.42), while overweight was also associated with an attenuated, yet significantly elevated risk (HR1.58, 95% CI 1.28 to 1.96).3 Further, in an analysis of the Nurses’ Health Study and Physicians’ Health Study, obesity in early adulthood was associated with an increased …

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    Footnotes

    • Contributors JAW is the sole contributor.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

    • Provenance and peer review Commissioned; internally peer reviewed.

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