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Cardiac rhythm management
103 Incidence of tricuspid regurgitation in his-bundle pacing
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  1. Jahanzeb Malik1,
  2. Syed Muhammad Jawad Zaidi2,
  3. Danish Iltaf Satti3
  1. 1Rawalpindi Institute of Cardiology, Rawal Road, Rawalpindi, 46000, Pakistan
  2. 2Rawalpindi Medical University
  3. 3Cardiovascular Analytics Group, Hong Kong China-UK collaboration

Abstract

Objective This systematic review aims to explore an association of new TR and its quantification in patients undergoing his-bundle pacing (HBP).

Methods A literature review was conducted using Mesh terms (His-bundle pacing, tricuspid regurgitation, tricuspid valve incompetence, etc.) in PubMed, EMBASE, Web of science CINAHL, and the Cochrane Library till October 2021. Relevant studies evaluating tricuspid regurgitation in HBP were included and information regarding TR and its related factors (ejection fraction (EF) and New York Heart Association (NYHA) class) were retrieved from the eligible studies.

Results Out of 196 articles, 10 studies met the inclusion criteria that included 546 patients with HBP. The mean age of the patients ranged between 61.2±12.3 to 75.1±7.9 years with 54.1% males. The implant success rate was 79.2%. Only one study reported a 5% incidence of TR while 9 studies reported no new TR after HBP. Two studies reported an average TR grade of at least 1 at baseline and <1 and another study reported improvement from moderate to mild TR grade in 7 patients and decreased TR grade from severe to moderate in 2 patients. Eight studies reported significant improvement in EF after HBP while 5 studies reported improvement in NYHA class.

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Conclusion HBP causes improvement in TR grade, EF, and NYHA class after HBP for cardiac resynchronization therapy (CRT) as well as an atrioventricular block (AVB). Further studies in the form of randomized controlled trials are required to further evaluate the effect of HBP on tricuspid valve functioning.

Conflict of Interest None

  • valvular heart disease
  • tricuspid anomaly
  • left bundle branch block

https://doi.org/10.1136/heartjnl-2022-BCS.103

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