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18 Exploring the validity of VentriJect Seismofit® for estimating peak oxygen uptake in people with coronary heart disease
  1. Anna Myers1,
  2. Ali Ali2,
  3. Nik Kudiersky1,
  4. Peter Søgaard3,
  5. Samuel Schmidt4,
  6. Wilfrid Girard5,
  7. Alasdair O’Doherty6,
  8. Simon Nichols1
  1. 1Advanced Wellbeing Research Centre, Sheffield Hallam University, Olympic Legacy Park, Sheffield, S9 3TU
  2. 2Sheffield Teaching Hospitals NHS, Foundation Trust, Sheffield, S10 2JF
  3. 3Aalborg University Hospital, Hobrovej 18-22 9100 Aalborg, Denmark
  4. 4Department of Health Science and Technology, Aalborg University, Frederik Beyers Vej 7D2, 9220 Aalborg Øst, Denmark
  5. 5VentriJect, Ryvangs Allé 81, 2900 Hellerup, Copenhagen, Denmark
  6. 6Department of Sport, Exercise and Rehabilitation, 234 Northumberland Building, Northumbria University, NE1 8ST


Background Peak oxygen uptake (&Vdot;O2peak) predicts all-cause mortality and can indicate the effectiveness of exercise-based cardiovascular rehabilitation (CR) in people living with coronary heart disease (CHD). Maximal cardiopulmonary exercise testing (CPET), the gold standard method of measuring &Vdot;O2peak, is expensive, time-consuming, and rarely used in CR. Furthermore, current methods to estimate &Vdot;O2peak in CR lack accuracy. A promising new device, that uses a quick (5-minute) resting seismocardiography measurement within an algorithm to estimate &Vdot;O2peak, is strongly associated with &Vdot;O2peak in healthy people (r = .90). However, the validity of VentiJect Seismofit in CHD has not been investigated.

Aim To explore the validity of the existing Ventriject Seismofit algorithm for predicting &Vdot;O2peak in people with CHD.

Methods Between August and November 2022, up to 24 participants aged ≥18 years, with a history of CHD and currently enrolled in community-based phase IV CR will be recruited. Participants will have their &Vdot;O2peak estimated using the VentriJect Seismofit (twice 20 minutes apart to assess repeatability), complete a maximal CPET on a cycle ergometer followed by a brief questionnaire about their experience of participating in a maximal CPET, and the VentriJect Seismofit device measurement.

Results Results from this study will be used to assess the validity of the current VentriJect Seismofit algorithm, for estimating &Vdot;O2peak in individuals with CHD. It will also assess the repeatability of the VentriJect Seismofit &Vdot;O2peak estimate in this population. Qualitative feedback will provide insight into participants perceptions of participating in a maximal CPET and having &Vdot;O2 peak measurements taken by VentriJect Seismofit.

Conclusion Data from this exploratory validation study will support future grant application to conduct a definitive validation study in people with CHD. If the device is demonstrated to provide an accurate and reliable estimate of &Vdot;O2peak in this population, it would represent a convenient and cost-effective method to be widely implemented in cardiac rehabilitation programmes.

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