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- Published on: 19 November 2024
- Published on: 19 November 2024SCD linked to multiple variables and risk factors
The health and wellbeing of an individual are shaped by many factors. Although this valuable study (1) focusses on elevated risk of sudden cardiac death (SCD) in patients with psychiatric disorders, and adjusts for age, sex and comorbidities, multiple other variables and risk factors were not considered; these may be outside of the remit of this study.
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Multiple variables and multiple other risk factors may interact, and interplay, all of which could affect the outcome of SCD in patients with psychiatric disorders. These include genetic factors, family history of cardiovascular disease and a personal history of cardiovascular diseases. Multiple cardiometabolic risk factors (risk factors include hypertension, diabetes, elevated cholesterol/ lipid levels and smoking) predisposes individuals to SCD.
The health of respiratory system and other vital organs (liver, kidneys, gut health) can modulate or indirectly affect cardiometabolic disease, which can lead to SCD. For example, COPD have a 34% increased risk of SCD overall, but the risk almost doubles more than five years after first being diagnosed with COPD. The risk of SCD increases more than three-fold after five years, in COPD patients who have frequent exacerbations (2).
Although the above-named risk factors shape the outcome of cardiovascular diseases and SCD, the most important variables are related to the social determinants of health (SDH). The health and wellbeing of an individual are shaped by SDH....Conflict of Interest:
None declared.