Article Text

Download PDFPDF

Mechanism of mitral regurgitation in hypertrophic obstructive cardiomyopathy
  1. R. B. Pridie,
  2. C. M. Oakley
  1. Department of Diagnostic Radiology, The London Hospital, London E.1
  2. Department of Medicine (Clinical Cardiology), Royal Postgraduate Medical School, London W.12


    Echocardiography of the mitral valve in patients with hypertrophic obstructive cardiomyopathy has revealed an abnormal pattern of movement. The abnormality is characteristic, readily recognized, and can be explained in anatomical and physiological terms. It consists of a sharp reopening of the valve during systole when it should normally remain in the fully closed position. This abnormal movement mirrors the mid-systolic onset of both outflow tract obstruction and mitral regurgitation. It was only absent in the two patients with the disease in whom both mitral regurgitation and outflow tract obstruction were also absent. A second and less striking abnormality was a reduced diastolic closure similar to that seen in mitral stenosis and attributed to slow left ventricular filling. The echo from the septum is also unduly prominent.

    Statistics from


    • Supported by a grant from the British Heart Foundation.

    • * Based on a paper given to the British Cardiac Society on 5 December 1968.

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.