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Prenylamine-induced ventricular tachycardia and syncope controlled by ventricular pacing.
  1. E Grenadier,
  2. S Keidar,
  3. G Alpan,
  4. A Marmor,
  5. A Palant


    We describe eight patients treated for angina with prenylamine who developed life-threatening ventricular arrhythmias after QT interval prolongation. When prenylamine administration was stopped QT interval shortened to within normal values, while the ventricular arrhythmias were controlled by a temporary ventricular pacemaker and disappeared after several days. We stress the importance of surveillance of the QT interval and ventricular arrhythmias in patients receiving long-term treatment with prenylamine.

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