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Haemodynamic effects of prostacyclin (PGI2) in pulmonary hypertension.
  1. D N Guadagni,
  2. H Ikram,
  3. A H Maslowski


    An infusion of prostacyclin (PGI2) in four patients with pulmonary hypertension resulted in a dose-related decrease in the systemic and pulmonary vascular resistance and an increase in cardiac output. No selectivity for the pulmonary vasculature was observed and the drug was not therapeutically beneficial.

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