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Rash after treatment with anistreplase.
  1. N Burrows,
  2. R R Jones
  1. Department of Dermatology, Ealing Hospital, Southall, Middlesex.


    A palpable purpura developed on the legs and lower abdomen of a woman of 54 five days after she was treated with anistreplase anisoylated plasminogen streptokinase activator complex (APSAC) for an acute myocardial infarction. Histological examination of a skin biopsy specimen taken 6 days after treatment showed leucocytoclastic vasculitis. The rash resolved within two weeks and there were no other complications.

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