Effect of early intravenous heparin on coronary patency, infarct size, and bleeding complications after alteplase thrombolysis: results of a randomised double blind European Cooperative Study Group trial.

D P de Bono; M L Simoons; J Tijssen; A E Arnold; A Betriu; C Burgersdijk; L López Bescos; E Mueller; M Pfisterer; F Van de Werf

doi:10.1136/hrt.67.2.122

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Research Article

Effect of early intravenous heparin on coronary patency, infarct size, and bleeding complications after alteplase thrombolysis: results of a randomised double blind European Cooperative Study Group trial.

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	Abstract	Full	Pdf
Jan 1999	1	0	0
Mar 1999	1	0	0
May 1999	1	0	0
Jun 1999	1	0	0
Jul 1999	1	0	0
Aug 1999	4	0	0
Jan 2000	1	0	0
Mar 2000	1	0	0
Apr 2000	2	0	0
Oct 2000	1	0	0
Nov 2000	1	0	0
Feb 2001	2	0	0
May 2001	1	0	0
Jun 2001	1	0	0
Jul 2001	9	0	0
Aug 2001	2	0	0
Oct 2001	3	0	0
Mar 2002	2	0	0
Apr 2002	2	0	0
May 2002	1	0	0
Jun 2002	5	0	0
Jul 2002	1	0	0
Sep 2002	2	0	0
Oct 2002	1	0	0
Nov 2002	1	0	0
Dec 2002	5	0	0
Jan 2003	9	0	0
Mar 2003	1	0	0
Jul 2003	4	0	0
Aug 2003	11	0	0
Sep 2003	16	0	0
Oct 2003	10	0	0
Nov 2003	10	0	0
Dec 2003	10	0	0
Jan 2004	10	0	0
Feb 2004	5	0	0
Mar 2004	12	0	0
Apr 2004	11	0	0
May 2004	9	0	0
Jun 2004	11	0	0
Jul 2004	14	0	0
Aug 2004	7	0	0
Sep 2004	4	0	0
Oct 2004	7	0	0
Nov 2004	7	0	0
Dec 2004	7	0	0
Jan 2005	26	0	0
Feb 2005	20	0	0
Mar 2005	11	0	0
Apr 2005	5	0	0
May 2005	6	0	0
Jun 2005	5	0	0
Jul 2005	4	0	0
Aug 2005	3	0	0
Sep 2005	7	0	0
Oct 2005	6	0	0
Nov 2005	4	0	0
Dec 2005	7	0	0
Jan 2006	6	0	0
Feb 2006	7	0	0
Mar 2006	3	0	0
Apr 2006	11	0	0
May 2006	5	0	0
Jun 2006	4	0	0
Jul 2006	3	0	0
Aug 2006	8	0	0
Sep 2006	3	0	0
Oct 2006	1	0	0
Nov 2006	4	0	0
Dec 2006	3	0	0
Jan 2007	6	0	0
Feb 2007	6	0	0
Mar 2007	19	0	0
Apr 2007	5	0	0
May 2007	3	0	0
Jun 2007	9	0	0
Jul 2007	7	0	0
Sep 2007	13	0	0
Oct 2007	22	0	3
Nov 2007	19	0	3
Dec 2007	6	0	3
Jan 2008	13	0	3
Feb 2008	7	0	0
Mar 2008	14	0	3
Apr 2008	12	0	7
May 2008	13	0	7
Jun 2008	6	0	0
Jul 2008	5	0	5
Aug 2008	10	0	2
Sep 2008	8	0	3
Oct 2008	9	0	3
Nov 2008	10	0	5
Dec 2008	5	0	1
Jan 2009	3	0	1
Feb 2009	10	0	5
Mar 2009	9	0	2
Apr 2009	4	0	2
May 2009	5	0	1
Jun 2009	9	0	3
Jul 2009	9	0	0
Aug 2009	9	0	2
Sep 2009	17	0	4
Oct 2009	14	0	3
Nov 2009	15	0	2
Dec 2009	10	0	0
Jan 2010	3	0	2
Feb 2010	9	0	1
Mar 2010	11	0	1
Apr 2010	7	0	2
May 2010	2	0	1
Jun 2010	12	0	6
Jul 2010	8	0	3
Aug 2010	134	0	21
Sep 2010	301	0	38
Oct 2010	105	0	13
Nov 2010	9	0	0
Dec 2010	6	0	2
Jan 2011	11	0	3
Feb 2011	18	0	2
Mar 2011	26	0	8
Apr 2011	14	0	19
May 2011	8	0	1
Jun 2011	21	0	8
Jul 2011	19	0	13
Aug 2011	26	0	2
Sep 2011	26	0	10
Oct 2011	25	0	13
Nov 2011	14	0	4
Dec 2011	13	0	20
Jan 2012	12	0	26
Feb 2012	13	0	25
Mar 2012	16	0	26
Apr 2012	10	0	24
May 2012	12	0	30
Jun 2012	8	0	31
Jul 2012	14	0	34
Aug 2012	15	0	56
Sep 2012	37	0	60
Oct 2012	13	0	36
Nov 2012	36	0	33
Dec 2012	39	0	10
Jan 2013	105	0	4
Feb 2013	117	0	1
Mar 2013	130	0	6
Apr 2013	25	0	2
May 2013	11	0	7
Jun 2013	27	0	3
Jul 2013	25	2	3
Aug 2013	171	0	1
Sep 2013	238	0	2
Oct 2013	147	0	2
Nov 2013	38	0	8
Dec 2013	9	0	2
Jan 2014	12	0	5
Feb 2014	18	0	9
Mar 2014	15	0	8
Apr 2014	17	0	4
May 2014	15	0	3
Jun 2014	13	0	3
Jul 2014	21	1	7
Aug 2014	24	0	3
Sep 2014	17	0	1
Oct 2014	15	0	5
Nov 2014	8	0	3
Dec 2014	12	0	6
Jan 2015	15	0	8
Feb 2015	9	0	5
Mar 2015	13	0	5
Apr 2015	8	0	5
May 2015	15	0	3
Jun 2015	11	0	14
Jul 2015	7	0	2
Aug 2015	23	0	5
Sep 2015	15	0	4
Oct 2015	14	0	2
Nov 2015	5	0	2
Dec 2015	7	0	4
Jan 2016	8	0	2
Feb 2016	16	0	6
Mar 2016	5	0	4
Apr 2016	6	0	2
May 2016	8	0	7
Jun 2016	5	0	4
Jul 2016	12	0	10
Aug 2016	14	0	1
Sep 2016	9	0	1
Oct 2016	11	0	2
Nov 2016	11	0	2
Dec 2016	17	0	1
Jan 2017	18	0	3
Feb 2017	13	0	6
Mar 2017	11	0	1
Apr 2017	16	0	0
May 2017	16	0	1
Jun 2017	19	0	3
Jul 2017	21	0	1
Aug 2017	38	0	1
Sep 2017	34	0	4
Oct 2017	28	0	1
Nov 2017	14	0	1
Dec 2017	34	0	5
Jan 2018	20	0	6
Feb 2018	34	0	2
Mar 2018	30	0	0
Apr 2018	36	0	5
May 2018	26	0	2
Jun 2018	12	0	2
Jul 2018	26	0	2
Aug 2018	36	0	3
Sep 2018	12	0	1
Oct 2018	14	0	0
Nov 2018	10	0	0
Dec 2018	10	0	0
Jan 2019	94	0	1
Feb 2019	26	0	1
Mar 2019	24	0	3
Apr 2019	18	0	6
May 2019	20	0	4
Jun 2019	22	0	7
Jul 2019	8	0	5
Aug 2019	14	0	1
Sep 2019	12	0	4
Oct 2019	12	0	1
Nov 2019	12	0	8
Dec 2019	14	0	1
Jan 2020	18	0	5
Feb 2020	12	0	3
Mar 2020	6	0	3
Apr 2020	14	0	5
May 2020	26	0	16
Jun 2020	12	0	1
Jul 2020	28	0	8
Aug 2020	18	0	8
Sep 2020	28	0	0
Oct 2020	22	0	7
Nov 2020	4	0	3
Dec 2020	14	0	2
Jan 2021	38	0	2
Feb 2021	6	0	2
Mar 2021	16	0	5
Apr 2021	18	0	2
May 2021	6	0	2
Jun 2021	0	0	4
Jul 2021	0	0	6
Aug 2021	0	0	11
Sep 2021	0	0	6
Oct 2021	14	0	16
Nov 2021	22	0	16
Dec 2021	18	0	2
Jan 2022	32	0	6
Feb 2022	21	0	4
Mar 2022	9	0	2
Apr 2022	21	0	6
May 2022	18	0	8
Jun 2022	22	0	3
Jul 2022	20	0	1
Aug 2022	68	0	9
Sep 2022	48	0	13
Oct 2022	40	0	8
Nov 2022	28	0	7
Dec 2022	40	0	5
Jan 2023	32	0	4
Feb 2023	78	0	3
Mar 2023	44	0	3
Apr 2023	14	0	0
May 2023	20	0	9
Jun 2023	16	0	1
Jul 2023	42	0	10
Aug 2023	68	0	5
Sep 2023	18	0	1
Oct 2023	28	0	4
Nov 2023	12	0	0
Dec 2023	50	0	1
Jan 2024	32	0	2
Feb 2024	44	0	0
Mar 2024	22	0	1
Apr 2024	26	0	0
May 2024	35	0	0
Jun 2024	22	0	2
Jul 2024	40	0	0
Aug 2024	30	0	1
Total	5462	3	1202

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