Article Text

Download PDFPDF

Restrictive and hypertrophic cardiomyopathies in Noonan syndrome: the overlap syndromes.
  1. P. T. Wilmshurst,
  2. D. Katritsis
  1. Department of Cardiology, Onassis Cardiac Surgery Centre, Athens, Greece.


    A woman with Noonan syndrome had clinical and haemodynamic features of restrictive cardiomyopathy. There was no ventricular hypertrophy on echocardiography but myocardial biopsies showed myocyte hypertrophy without pathological disarray. This case illustrates the overlap of the cardiac phenotypes of Noonan syndrome, restrictive cardiomyopathy, and hypertrophic cardiomyopathy.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.