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Cardiac valve invasion in chronic adult T cell leukaemia
  1. J Takataa,
  2. H Taguchib,
  3. I Miyoshib,
  4. Y L Doia
  1. aDepartment of Medicine and Geriatrics, Kochi Medical School, Oko-cho, Nankoku-shi, Kochi 783, Japan, bThird Department of Medicine, Kochi Medical School
  1. Dr Doi.

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The cause of adult T cell leukaemia (ATL)1 is human T cell leukaemia virus type I (HTLV-I), which was discovered in 1980.2 This virus is endemic in southwestern Japan, the Caribbean, Africa, and South America. However, cardiac valve involvement by ATL cells is extremely rare3 and there is no previous echocardiographic evidence for this involvement. We present serial echocardiographic observations in a patient with chronic ATL in whom leukaemic involvement of the mitral valve showed pronounced improvement after chemotherapy.

A 58 year old woman was admitted because of two previous episodes of acute heart failure. On examination, generalised skin eruptions and lymphadenopathies …

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