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Persistent pulmonary hypertension of the newborn associated with pulmonary atresia and intact interventricular septum

Abstract

Neonates with pulmonary atresia and intact interventricular septum (PAIVS) do not have pulmonary vascular disease secondary to their heart abnormality. Persistent pulmonary hypertension of the newborn has not been described in association with this condition. The case is reported of a female neonate born with PAIVS, who preoperatively had no clinical evidence or any risk factors for persistent pulmonary hypertension of the newborn, but whose postoperative course was highly suggestive of persistent pulmonary hypertension; necropsy confirmed the features of pulmonary vascular disease.

  • persistent pulmonary hypertension
  • pulmonary atresia and intact ventricular septum
  • pulmonary vascular disease
  • surgery
  • congenital heart defects
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