Article Text

Prognostic significance of electrical alternans vsignal averaged ECG in predicting the outcome of electrophysiological testing and arrhythmia-free survival
  1. H ECTOR
  1. University Hospital Gasthuisberg
  2. Department of Cardiology
  3. B-3000 Leuven, Belgium
  4. email: Hugo.Ector@med.kuleuven.ac.be

    Statistics from Altmetric.com

    Editor,—I was intrigued by the paper “Prognostic significance of electrical alternans versus signal averaged electrocardiography in predicting the outcome of electrophysiological testing and arrhythmia-free survival” by Armoundaset al.1 In a time of statistics and prediction of important outcome events the reader has to pay much attention to the literature.

    The conclusion “T wave alternans was a highly significant predictor of the outcome of electrophysiological testing and arrhythmia-free survival” is wrong; the positive predictive values are very low with very large confidence limits. The conclusion should be “There is a significant association between T wave alternans (TWA) and the outcome of electrophysiological (EP) testing. With single sided tests of significance there was a difference in arrhythmia-free survival for EP negative v EP positive …

    View Full Text

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.