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Long term consequences of regressed coronary aneurysms after Kawasaki disease: vascular wall morphology and function
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  • Published on:
    Re: Coronary endothelial dysfunction after Kawasaki disease
    • Masahiro Ishii, Department of Pediatrics
    • Other Contributors:
      • "Motofumi Iemura, Hirohisa Kato"

    Dear Editor:

    We appreciate the kind comments of Dr Mitani regarding our article in the March 2000 issue of Heart and for sharing their experiences with us.[1]

    In group 1 and 2 patients who had regressed coronary aneurysm after Kawasaki disease, there was significantly more vascular constriction with acetylcholine and poorer dilatation with isosorbide dinitrate at the regressed site, than in group 3 patient...

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    Conflict of Interest:
    None declared.
  • Published on:
    Coronary Endothelial Dysfunction after Kawasaki Disease
    Dear Editor

    Iemura et al's hypothesis that endothelial dysfunction is associated with coronary aneurysms which have regressed after Kawasaki disease (KD) is interesting[1]; however, there are two issues with respect to their study design that need to be considered, in addition to the issues reported before.[2, 3]

    (1) Is endothelial dysfunction associated with regressed coronary aneurysms per se late after KD?

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    Conflict of Interest:
    None declared.