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Homocysteine and coronary heart disease in the Caerphilly cohort: a 10 year follow up
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  • Published on:
    Homocysteine and coronary heart disease - Authors' reply
    • Una B Fallon, Wellcome Training Fellow in Clinical Epidemiology
    Dear Editor

    We wish to thank Professor Wald and colleagues for highlighting an error in our paper.1 We misreported the standard deviation for total plasma homocysteine concentration (tHcy) in table 2 so that this was, as Wald infers, too small. This error occurred because our analyses were based on the log transformed data. The true value of the back-transformed standard deviation is between 3.4 and 4.8...

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    Conflict of Interest:
    None declared.
  • Published on:
    Homocysteine and coronary heart disease
    Dear Editor:

    Fallon and colleagues reported no association between serum homocysteine and coronary heart disease in the Caerphilly cohort study,[1] and contrasted their result with the "positive results" shown in other studies including our own BUPA (British United Provident Association) cohort study of 21,520 men.[2] Fallon and colleagues may be incorrect in interpreting their results as negative. They express them as...

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    Conflict of Interest:
    None declared.