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Trends in mortality from cardiovascular and cerebrovascular diseases in Europe and other areas of the world
  1. F Levi1,
  2. F Lucchini1,
  3. E Negri2,
  4. C La Vecchia2,*
  1. 1Unité d'épidémiologie du cancer and Registres vaudois et neuchâtelois des tumeurs, Institut universitaire de médecine sociale et préventive, Centre Hospitalier Universitaire Vaudois, Falaises 1, 1011 Lausanne, Switzerland
  2. 2Istituto di Ricerche Farmacologiche “Mario Negri”, Via Eritrea 62, 20157 Milano, Italy
  1. Correspondence to:
    Dr F Levi, Registre vaudois des tumeurs, CHUV-Falaises 1, CH-1011 Lausanne, Switzerland;


Objective: To analyse trends in mortality from coronary heart disease (CHD) and cerebrovascular disease (CVD) over the period 1965 to 1998 in the European Union, other European countries, the USA, and Japan.

Methods and results: Data were derived from the World Health Organization database. In the European Union, CHD mortality in men rose from 146/100 000 in 1965–9 to 163/100 000 in 1975–9 and declined thereafter to 99/100 000 in 1995–8 (−39%). In women, the fall was from 70 to 45/100 000 (−36%). A > 55% decline in CVD was registered in both sexes. In eastern Europe, mortality from both CHD and CVD rose up to the early 1990s but has declined over the past few years in Poland and the Czech Republic. In the Russian Federation during 1995–8, mortality rates from CHD reached 330/100 000 men and 154/100 000 women and mortality rates from CVD were 203/100 000 men and 150/100 000 women—that is, they were among the highest rates worldwide. In the USA and Japan, long term trends were favourable for both CHD and CVD.

Conclusions: Trends in mortality from CHD and CVD were favourable in several developed areas of the world, but there were major geographical differences. In a few eastern European countries, mortality from CHD and CVD remains exceedingly high.

  • cerebrovascular diseases
  • coronary heart diseases
  • mortality
  • trends
  • CHD, coronary heart disease
  • CVD, cerebrovascular disease
  • ICD, International classification of diseases
  • WHO, World Health Organization

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  • * Also the Istituto di Statistica Medica e Biometria, Università degli Studi di Milano, Via Venezian 1, 20133 Milano, Italy

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