Article Text

Download PDFPDF
Non-invasive automated assessment of the ratio of pulmonary to systemic flow in patients with atrial septal defects by the colour Doppler velocity profile integration method
  1. Y Ueda1,
  2. T Hozumi2,
  3. K Yoshida3,
  4. H Watanabe2,
  5. T Akasaka3,
  6. T Takagi1,
  7. A Yamamuro1,
  8. S Homma4,
  9. J Yoshikawa2
  1. 1Division of Cardiology, Kobe General Hospital, Kobe, Japan
  2. 2Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, Osaka, Japan
  3. 3Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan
  4. 4Division of Cardiology, Columbia University, New York, USA
  1. Correspondence to:
    Dr Takeshi Hozumi, Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan;
    thozumi{at}med.osaka-cu.ac.jp

Abstract

Background: The recent introduction of the automated cardiac flow measurement (ACM) method, using spatiotemporal integration of the Doppler velocity profile, provides a quick and accurate automated calculation of cardiac output.

Objective: To evaluate the ACM method against oximetry during cardiac catheterisation for estimating the Qp/Qs (pulmonary to systemic flow) ratio in patients with an atrial septal defect.

Methods: Left and right ventricular stroke volume (LVSV, RVSV) were calculated by ACM in 22 patients with an atrial septal defect who underwent cardiac catheterisation and in 11 patients without heart disease (control group). With ACM, the Qp/Qs ratio was estimated from RVSV divided by LVSV. In the patients with an atrial septal defect, the Qp/Qs ratio was assessed by oximetry at the time of cardiac catheterisation.

Results: There was a good correlation between LVSV and RVSV obtained by ACM in the control group (r = 0.98, y = 0.97x + 0.25, SEE = 2.9 ml). The mean difference between LVSV and RVSV by ACM was −1.25 (2.76) ml. The Qp/Qs ratio obtained by ACM in the control group was 0.98 (0.06). The Qp/Qs ratio in patients with an atrial septal defect was significantly higher than in the control group (3.11 (1.20), p < 0.001). ACM determination of the Qp/Qs ratio correlated well with oximetry determination (r = 0.86, y = 0.75x + 0.55, SEE = 0.64). The mean difference between ACM and oximetry for the measurement of the Qp/Qs ratio was −0.28 (0.69).

Conclusions: The newly developed ACM method is clinically useful for non-invasive automated estimations of the Qp/Qs ratio in patients with an atrial septal defect.

  • echocardiography
  • pulmonary to systemic flow
  • atrial septal defect
  • colour Doppler
  • ACM, automated cardiac flow measurement
  • LVSV, left ventricular stroke volume
  • Qp/Qs, pulmonary to systemic flow
  • RVSV, right ventricular stroke volume

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes