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Nitric oxide and myocardial function in heart failure: friend or foe?
  1. J M Cotton,
  2. M T Kearney,
  3. A M Shah
  1. Department of Cardiology, Guy’s King’s & St Thomas’s School of Medicine, King’s College London (Denmark Hill Campus), London, UK
  1. Correspondence to:
    Professor Ajay M Shah, Department of Cardiology, Guy’s King’s & St Thomas’s School of Medicine, Bessemer Road, London SE5 9PJ, UK;
    ajay.shah{at}kcl.ac.uk

Abstract

There is good evidence that nitric oxide has important autocrine/paracrine effects in the myocardium, serving to optimise and fine tune cardiac function

  • nitric oxide
  • heart failure
  • myocardial function
  • DCM, dilated cardiomyopathy
  • NO, nitric oxide
  • NOS, NO synthase
  • eNOS, endothelial NOS
  • iNOS, inducible NOS
  • nNOS, neuronal NOS
  • SR, sarcoplasmic reticulum
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