Article Text

Download PDFPDF
Moderated presentations

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


ZI Khan, GA Wharton, GJ WilliamsYorkshire Heart Centre, Leeds, UK

Introduction: Strain imaging provides information on local myocardial deformation. Global left (LV) & right (RV) ventricular function is impaired to varying degrees in surgically repaired tetralogy of Fallot (rTOF) patients. Using strain imaging we assessed the local deformation characteristics of different regions of the LV+RV.

Method: rTOF patients were compared to normal controls. All subjects were imaged in the apical 2+4-chamber views superimposed with tissue Doppler imaging data. Longitudinal strain was calculated off line by placing the sample volume in the mid-ventricular and basal segments of the lateral, septal, inferior & anterior walls of the LV & the free wall of the RV. The results were averaged from 3 cardiac cycles.

Results are expressed as mean (±SD). 24 rTOF patients were compared to 15 age matched normal controls (31.38±10.38yrs v 32.07±9.87yrs, p=NS). There was no significant difference in strain between the basal+mid regions of the LV or RV in the normal population. In the rTOF group, strain was greatest at the base of the heart compared to the mid region in the RV (24.10±10.41% vs 17.3±9.05%, p=0.03), septum (25.75±8.32% vs 17.06± 5.66%, p<0.001), lateral (19.92±6.73% vs 15.07±6.93%, p<0.04), inferior (20.73±7.44% vs 15.86±5.31%, p<0.05) & anterior (22.23±8.56% vs 16.69±5.38%, p<0.05) walls of the LV. Basal strain of the LV was similar in both groups. However mid-septal (16.59±5.26% vs 24.07±10.54%, p=0.02), mid-lateral (14.97±7.06% vs 21.12 ±6.36%, p<0.01), mid-inferior (15.97±5.46% vs 21.53±6.92, p<0.02) & mid-anterior (16.31±5.35% vs 20.75±5.50, p=0.04) strain were significantly less. RV strain was similar to that of the normal population at both the basal & mid regions (24.65±10.31% vs 29.93 ±13.43%, p=NS and 16.99±9.14% vs 22.27±11.74%, p=NS, respectively).

Conclusion: Myocardial deformation of the RV is normal in rTOF subjects. However LV deformation is reduced. The pattern of abnormal …

View Full Text