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Acquired combined immunodeficiency associated with protein losing enteropathy complicating Fontan operation
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  • Published on:
    PLE after Fontan Operation and Immunological Dysfunction.

    Dear Editor

    The response by Prof Tarnok [1] is both interesting and thought provoking. The suggestion of mature immune system in this group will need further clarification. Thymectomy is often performed as part of their initial surgery; hence the nature of T cell response in this group may be different from other patients with PLE. This is further complicated by the presence of heterotaxy and asplenia. I have encoun...

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    Conflict of Interest:
    None declared.
  • Published on:
    Does PLE after Fontan palliation refer to immunodeficiency?

    Dear Editor

    We have read with great interest the manuscript by Chakrabarti et al.[1] on immunodeficiency in patients suffering from protein losing enteropathy (PLE) after Fontan palliation. The authors reported of lymphopenia and T-lymphocyte loss in two children with PLE. The infrequency of this syndrome and the even rarer immunological investigation of affected patients makes these observations very pre...

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    Conflict of Interest:
    None declared.