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β Thalassaemia major and severe left ventricular dysfunction
  1. M D Sosin,
  2. S Handa,
  3. D L Connolly,
  4. R Davis
  1. r.davis@swbh.nhs.uk

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Patients with β thalassaemia major are dependent upon regular blood transfusions, and consequently are subjected to a large iron load. Accumulation of excess iron leads to heart failure. Iron chelation therapy can delay this process, but compliance is commonly poor. Severe cardiac failure in iron overloaded patients with β thalassaemia major has …

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