Article Text

The debate on public place defibrillators: charged but shockingly ill informed
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1. J P Pell
1. Correspondence to:
Dr Jill Pell
Greater Glasgow NHS Board, Dalian House, 350 St Vincents Street, Glasgow, UK; jill.pellgghb.scot.nhs.uk

Abstract

There is growing interest in developing strategies which will enable defibrillation to be administered while waiting for the emergency medical service to arrive

• public place defibrillators
• ventricular fibrillation

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Nearly half of all deaths from cardiovascular disease are sudden and unexpected.1 Most sudden cardiac deaths occur before hospital admission. The delay from cardiopulmonary arrest to defibrillation is a significant independent predictor of survival.2 Two minutes after the arrest around two thirds of victims have rhythms amenable to defibrillation, but this percentage decreases rapidly with time. Obviously, it is imperative to minimise the delay from calling the emergency medical service to their arrival at the arrest scene. However, some delay is inevitable. Therefore, interest has grown in complementary strategies whereby defibrillation can be administered while waiting for the emergency medical service to arrive.

Individuals known to be at very high risk of arrest can be provided with implantable cardioverter-defibrillators or automated external defibrillators for their personal use. However, such individuals account for a small percentage of all pre-hospital arrests.3 Therefore, such strategies have relatively little impact at a population level. The American Heart Association has suggested a number of possible population strategies.4 Firstly traditional first responders, such as police and fire personnel, can be provided with automated external defibrillators and training in their use. Secondly, novel first responders can be identified and trained. One example includes the provision of defibrillators on aircraft for use by trained airline personnel. Thirdly, training can be given to groups of lay volunteers. Finally, it is possible to adopt an alternative approach by locating “intelligent” defibrillators in public places for use by lay bystanders with minimal or no training in their use. This approach is analogous to that adopted for fire extinguishers.

LOCATING DEFIBRILLATORS IN PUBLIC PLACES

Locating defibrillators in public places, such as airports, is associated with a high survival among individuals on whom they are used. For example, 70 automated defibrillators were located in three airports in Chicago, USA. Over the subsequent two years, 18 people were shocked for ventricular fibrillation (VF) and 10 (56%) survived.5 Unfortunately this study was typical of many in that the investigators were unable to provide meaningful comparative data. They compared their survival to the 2.9% survival reported in an 11 year old study.6 This very low figure was based on all arrests, rather than just VF arrests, and all locations, rather than just public places or airports. Therefore, the comparison was inappropriate. The choice of comparison group is critical if bias is to be avoided. Cardiac arrests that occur in public places are significantly more likely to be witnessed and, therefore, already have the shortest ambulance delays. Among arrests in public places, 12.8% are attended within three minutes compared with only 9.7% in more secluded locations.7 As a result, people who arrest in public places are already more likely to be shocked (72.9% v 56.2%) and, therefore, have the highest baseline survival (8.7% v 4.2%).7 People with the foresight to arrest in airports are more fortunate still since half of the “untrained bystanders” in Chicago airports had medical degrees!5

As with implantable defibrillators, public place defibrillators may have a limited impact at the population level. The vast majority of pre-hospital arrests occur in places completely unsuitable for locating public place defibrillators such as private homes and open countryside.7 Studies have consistently shown that only 16–18% of pre-hospital arrests occur in public places,7–9 and less than 2% of pre-hospital arrests occur in public places in which the frequency of arrests exceeds one every 10 years.8 Using data from the Heartstart Registry we were able to demonstrate that making defibrillators as ubiquitous as fire extinguishers would improve overall survival from non-crew witnessed arrests from 5.0% to only 6.5%.7 By contrast, providing defibrillators to the fire service, which already has a five minute response time, could potentially double overall survival.2

COST EFFECTIVENESS

Public place defibrillators are only one option among a number of potential strategies aimed at reducing time to defibrillation. Therefore, it is imperative to consider not only their clinical effectiveness but also their cost effectiveness. A few studies have attempted to calculate the cost effectiveness of public place defibrillators. However, all have been limited by a lack of data on either benefit or cost. Caffrey and colleagues used the data from the Chicago airports to calculate a cost per life gained.5 However, as already discussed, the increase in survival was exaggerated greatly by the choice of an inappropriate comparison group. In England, the Department of Health has committed more than £3 million (€4.3 million) to provide defibrillators in 72 public places. Woollard attempted to model the cost effectiveness of this strategy.10 However, a crucial assumption in his model was that 50% of all future public place arrests in the whole of England will occur in the 72 sites in which public place defibrillators will be located. The published evidence does not support this assumption.7–9

In the cost effectiveness model of public place defibrillators conducted by Nichol and colleagues, they assumed that the “density of distribution of defibrillators in a community was such that one device was available for each cardiopulmonary arrest that occurred in public”.11 However, they acknowledged having no data on the costs needed to achieve this level of coverage. They included an additional cost per arrest of only US$1200 in their public place defibrillator model compared with an additional cost per arrest of$3300 in a separate police first responder model. Only \$300 of the police cost was attributed to training. Hence, after subtracting the costs of training, the additional cost per arrest used in the police model was still 2.5 times higher than that used in the public place defibrillator model.

The location of future arrests cannot be predicted accurately. Public place defibrillators are frequently carried on foot and can, therefore, cover only a small geographical area. By contrast, police vehicles can transport defibrillators rapidly across a much larger geographical area. Hence, public place defibrillators have to be distributed more densely to achieve the same level of coverage as a dynamically deployed system. Therefore, it is difficult to conceive how the cost per arrest of providing “one device...for each cardiac arrest that occurred in public” could be achieved more cheaply using public place defibrillators than a police first responder model.