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Primary pericardial mesothelioma presenting as pericardial constriction: a case report
  1. S Suman,
  2. P Schofield,
  3. S Large
  1. Departments of Cardiology and Cardiac Surgery, Papworth Hospital, Papworth, Cambridge, UK
  1. Correspondence to:
    Dr Shivani Suman
    Department of Cardiology, Papworth Hospital, Papworth, Cambridge, UK;


A 19 year old man presented with a six month history of chest pain, dyspnoea, and lethargy and was found on an echocardiogram to have a dilated left ventricle with a small pericardial effusion. Ramipril and a course of steroids were tried but serial echocardiograms showed a persistently thickened pericardium and slowly developing features of constriction. On computed tomography, a large mediastinal mass encasing the heart, along with para-aortic and paratracheal lymphadenopathy, was found. Right heart catheter studies showed equal pressures in all four chambers. His deteriorating clinical condition led to a pericardiectomy. Histology confirmed primary pericardial mesothelioma. The patient died soon after surgery.

  • primary pericardial mesothelioma

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