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The Fontan procedure has been extensively used for palliation of patients with univentricular heart defects. Thrombi and thromboembolic complications have been frequently reported after this operation. Magnetic resonance imaging (MRI) has been shown to be very useful in patients with congenital heart disease and also in the detection of intracardiac masses and thrombosis. We describe for the first time the ability of MRI to detect right heart thrombosis and monitor the effect of treatment in a Fontan patient.
A 29 year old Fontan patient presented with recent onset ankle oedema and pronounced asthenia. He had been treated with the Fontan procedure when he was 2 years old because of a double outlet right ventricle and transposition of the great vessels. MRI was performed by using a 1.5T imager (Intera, Philips Medical Systems) and a breath-hold fast field echo sequence (FFE). MRI showed a large, mobile right atrial mass attached to the free wall indicating the presence of a thrombus, and also detected the presence of endoluminal pulmonary arterial thrombi (upper panels—to view video footage go to http://www.heartjnl.com/supplemental). The patient was treated with oral anticoagulants and MRI was repeated after three months. A notable improvement in the patient’s clinical condition was reported, while the MRI showed that the pulmonary arterial clots and intracardiac thrombus had disappeared (lower panels—to view video footage go to http://www.heartjnl.com/supplemental).
After the Fontan procedure MRI may represent a valuable alternative to other imaging methods in detecting intracardiac thrombi and for monitoring their evolution after treatment. Particularly relevant is the ability of MRI to identify pulmonary artery thrombosis in such patients.
Please note that there are 2 video sequences that accompany this article
Files in this Data Supplement:
- [View Video] - Video Sequence 1 Breath hold FFE cine MRI in the axial plane through the right atrium and mitral valve showing a large mobile thrombus within the right atrial cavity. Note the slow flow present in the right atrium. File size: 212 KB
- [View Video]
Video Sequence 2 Breath hold FFE cine MRI in the axial plane showing right
pulmonary artery thrombosis partially occluding the vessel and
determining slowing of blood flow at this level
File size: 187 KB