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Three dimensional segmented myocardial perfusion images by selective intracoronary injection of contrast using 256 slice cone beam computed tomography
  1. N Funabashi1,
  2. K Yoshida1,
  3. H Tadokoro2,
  4. K Nakagawa1,
  5. N Komiyama1,
  6. K Odaka2,
  7. T Tsunoo2,
  8. S Mori2,
  9. M Endo2,
  10. S Tanada2,
  11. I Komuro1
  1. 1Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chiba, Japan
  2. 2National Institute of Radiological Sciences, Chiba, Japan
  1. Correspondence to:
    Nobusada Funabashi
    MD, Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba 260-8670, Japan;

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Information of the segmented left ventricular (LV) area supplied by every coronary artery is potentially useful for strategy and practice of percutaneous coronary intervention, coronary artery bypass surgery, or percutaneous transluminal septal myocardial ablation (PTSMA).1,2

Myocardial contrast echocardiography (MCE) with intracoronary contrast injection has been used to evaluate the segmented LV area supplied by a coronary artery but it is invasive and evaluation of myocardial enhancement by ultrasound contrast material may depend upon the skill of the investigator.1

With a prototype high speed cone beam computed tomography (CT) apparatus employing 256 detector rows (Athena, Sony-Toshiba), an entire heart can be imaged within a single gantry rotation.3,4 Using this technique, combined with selective intracoronary injection of contrast, we determined the segmented LV area supplied by every coronary artery selectively.


Two domestic pigs (20 kg each) were anaesthetised with isoflurane, and catheters positioned in the left anterior descending branch (LAD) of the coronary artery in pig 1 and the left circumflex branch (LCx) in pig 2, via the femoral arteries. The heart rate of pigs ranged between 70–80 beats per minute.

Scan conditions for the 256 slice cone beam CT were: 120 kV, 200 mA, 1.0 second exposure, 1.0 second gantry rotation time, 0.5 mm slice thickness, and 256×0.5 mm slice collimation. For comparison, those for the 16 slice multislice CT scanner routinely used at our institute (SOMATOM Sensation 16, Siemens) were: …

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