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Modern management of myocardial infarction: introduction
  1. C J Knight
  1. Correspondence to:
    Dr Charles J Knight
    Barts and the London Heart Centre, London Chest Hospital, Bonner Road, London E2 9JX, UK;

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It is not so very long ago that the treatment for a patient with myocardial infarction consisted of bed rest and analgesia. Myocardial destruction was observed but not modified by the cardiologist. The situation is very different at the start of the 21st century. Decades of large randomised clinical trials have informed physicians of the benefits of both pharmacological and mechanical methods of reperfusion to the great benefit of patients with acute coronary occlusion. It has become increasingly clear that to make a real impact on the prognosis of patients with myocardial infarction, a wide perspective is needed and the greatest successes have occurred when whole health care …

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