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Clinical significance of patent foramen ovale: introduction
  1. F A Flachskampf,
  2. W G Daniel
  1. Medizinische Klinik II, Universitätsklinik Erlangen, Germany
  1. Correspondence to:
    Professor Frank A Flachskampf

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Since Lechat’s and Webster’s seminal reports, the statistical association of cryptogenic stroke and patent foramen ovale (PFO) has intrigued both cardiologists and neurologists. Growing technical experience and improved percutaneous devices …

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