An 18 year old woman was admitted to hospital because of exertion dyspnoea for two months. The patient had undergone splenectomy because of thalassaemia major six years previously. Transthoracic echocardiographic examination revealed two mobile, homogenous masses suggesting thrombus or myxoma at two separate locations in the right atria. Both atrial and ventricular dimensions and functions were normal. A transoesophageal echocardiogram confirmed the presence of the two masses. The patient was referred for surgery. Histopathological examination of the specimen revealed an organised thrombus.

To our knowledge, this is the first report of a multifocal atrial thrombus occurring without any accompanying cardiac disease.