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Xanthine oxidase inhibition for chronic heart failure: is allopurinol the next therapeutic advance in heart failure?

Abstract

A substantial body of evidence has accumulated to suggest a role for the xanthine oxidase metabolic pathway in the pathophysiology of chronic heart failure and other cardiovascular diseases

  • BNP, brain natriuretic peptide
  • CHF, chronic heart failure
  • NO, nitric oxide
  • XO, xanthine oxidase
  • allopurinol
  • heart failure
  • xanthine oxidoreductase

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  • Miscellanea
    BMJ Publishing Group Ltd and British Cardiovascular Society